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Nat Rev Drug Discovery (2002) 1(5):34758
Evidence Ledger: What Each Major Claim Is Actually Based On Dose Numbers: What the Studies Actually Used The original Monnier work used intravenous infusion in rabbits at doses that, when scaled, fall roughly in the 25 to 60 nanomoles per kilogram range for producing measurable EEG changes
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According to the NewcastleOttawa Scale (NOS) for case-control studies (n = 2) (Yamane et al., 1995
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